John Wayne casserole is a Tex-Mex inspired casserole that layers taco-seasoned ground beef, veggies, cheese, and a creamy sauce over a biscuit dough base.
Believe it or not, the original recipe actually came from John Wayne—yes, the John Wayne.
Ground beef Taco seasoning Water Bisquick mix Mayonnaise Sour cream Sharp cheddar cheese Onion Green pepper Roma tomatoes Green chiles
Preheat your oven to 325ºF. Coat a 9×13-inch baking dish with non-stick cooking spray.